Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen.

Vardhana, Santosha A; Hwee, Madeline A; Berisa, Mirela; Wells, Daniel K; Yost, Kathryn E; King, Bryan; Smith, Melody; Herrera, Pamela S; Chang, Howard Y; Satpathy, Ansuman T; van den Brink, Marcel R M; Cross, Justin R; Thompson, Craig B.

Nat Immunol ; 21(9): 1022-1033, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32661364

2.

The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells.

King, Bryan; Boccalatte, Francesco; Moran-Crusio, Kelly; Wolf, Elmar; Wang, Jingjing; Kayembe, Clarisse; Lazaris, Charalampos; Yu, Xiaofeng; Aranda-Orgilles, Beatriz; Lasorella, Anna; Aifantis, Iannis.

Nat Immunol ; 17(11): 1312-1321, 2016 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-27668798

3.

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.

King, Bryan; Trimarchi, Thomas; Reavie, Linsey; Xu, Luyao; Mullenders, Jasper; Ntziachristos, Panagiotis; Aranda-Orgilles, Beatriz; Perez-Garcia, Arianne; Shi, Junwei; Vakoc, Christopher; Sandy, Peter; Shen, Steven S; Ferrando, Adolfo; Aifantis, Iannis.

Cell ; 153(7): 1552-66, 2013 Jun 20.

Artigo em Inglês | MEDLINE | ID: mdl-23791182

4.

High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down.

Li, Xiaoyi; Pritykin, Yuri; Concepcion, Carla P; Lu, Yuheng; La Rocca, Gaspare; Zhang, Minsi; King, Bryan; Cook, Peter J; Au, Yu Wah; Popow, Olesja; Paulo, Joao A; Otis, Hannah G; Mastroleo, Chiara; Ogrodowski, Paul; Schreiner, Ryan; Haigis, Kevin M; Betel, Doron; Leslie, Christina S; Ventura, Andrea.

Mol Cell ; 79(1): 167-179.e11, 2020 07 02.

Artigo em Inglês | MEDLINE | ID: mdl-32497496

5.

Yap/Taz promote the scavenging of extracellular nutrients through macropinocytosis.

King, Bryan; Araki, Jingwen; Palm, Wilhelm; Thompson, Craig B.

Genes Dev ; 34(19-20): 1345-1358, 2020 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-32912902

6.

TET1 is a tumor suppressor of hematopoietic malignancy.

Cimmino, Luisa; Dawlaty, Meelad M; Ndiaye-Lobry, Delphine; Yap, Yoon Sing; Bakogianni, Sofia; Yu, Yiting; Bhattacharyya, Sanchari; Shaknovich, Rita; Geng, Huimin; Lobry, Camille; Mullenders, Jasper; King, Bryan; Trimarchi, Thomas; Aranda-Orgilles, Beatriz; Liu, Cynthia; Shen, Steven; Verma, Amit K; Jaenisch, Rudolf; Aifantis, Iannis.

Nat Immunol ; 16(6): 653-62, 2015 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-25867473

7.

Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder.

Sikich, Linmarie; Kolevzon, Alexander; King, Bryan H; McDougle, Christopher J; Sanders, Kevin B; Kim, Soo-Jeong; Spanos, Marina; Chandrasekhar, Tara; Trelles, M D Pilar; Rockhill, Carol M; Palumbo, Michelle L; Witters Cundiff, Allyson; Montgomery, Alicia; Siper, Paige; Minjarez, Mendy; Nowinski, Lisa A; Marler, Sarah; Shuffrey, Lauren C; Alderman, Cheryl; Weissman, Jordana; Zappone, Brooke; Mullett, Jennifer E; Crosson, Hope; Hong, Natalie; Siecinski, Stephen K; Giamberardino, Stephanie N; Luo, Sheng; She, Lilin; Bhapkar, Manjushri; Dean, Russell; Scheer, Abby; Johnson, Jacqueline L; Gregory, Simon G; Veenstra-VanderWeele, Jeremy.

N Engl J Med ; 385(16): 1462-1473, 2021 10 14.

Artigo em Inglês | MEDLINE | ID: mdl-34644471

8.

Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement.

Barton, Linda S; Callahan, James F; Cantizani, Juan; Concha, Nestor O; Cotillo Torrejon, Ignacio; Goodwin, Nicole C; Joshi-Pangu, Amruta; Kiesow, Terry J; McAtee, Jeff J; Mellinger, Mark; Nixon, Christopher J; Padrón-Barthe, Laura; Patterson, Jaclyn R; Pearson, Neil D; Pouliot, Jeffrey J; Rendina, Alan R; Buitrago Santanilla, Alexander; Schneck, Jessica L; Sanz, Olalla; Thalji, Reema K; Ward, Paris; Williams, Shawn P; King, Bryan W.

Bioorg Med Chem ; 100: 117618, 2024 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-38309201

9.

Autism Spectrum Disorder: A Review.

Hirota, Tomoya; King, Bryan H.

JAMA ; 329(2): 157-168, 2023 01 10.

Artigo em Inglês | MEDLINE | ID: mdl-36625807

10.

GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2.

Ye, Jiangbin; Palm, Wilhelm; Peng, Min; King, Bryan; Lindsten, Tullia; Li, Ming O; Koumenis, Constantinos; Thompson, Craig B.

Genes Dev ; 29(22): 2331-6, 2015 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-26543160

11.

Erratum: TET1 is a tumor suppressor of hematopoietic malignancy.

Cimmino, Luisa; Dawlaty, Meelad M; Ndiaye-Lobry, Delphine; Yap, Yoon Sing; Bakogianni, Sofia; Yu, Yiting; Bhattacharyya, Sanchari; Shaknovich, Rita; Geng, Huimin; Lobry, Camille; Mullenders, Jasper; King, Bryan; Trimarchi, Thomas; Aranda-Orgilles, Beatriz; Liu, Cynthia; Shen, Steven; Verma, Amit K; Jaenisch, Rudolf; Aifantis, Iannis.

Nat Immunol ; 16(8): 889, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-26194287

12.

RIP3 induces apoptosis independent of pronecrotic kinase activity.

Mandal, Pratyusha; Berger, Scott B; Pillay, Sirika; Moriwaki, Kenta; Huang, Chunzi; Guo, Hongyan; Lich, John D; Finger, Joshua; Kasparcova, Viera; Votta, Bart; Ouellette, Michael; King, Bryan W; Wisnoski, David; Lakdawala, Ami S; DeMartino, Michael P; Casillas, Linda N; Haile, Pamela A; Sehon, Clark A; Marquis, Robert W; Upton, Jason; Daley-Bauer, Lisa P; Roback, Linda; Ramia, Nancy; Dovey, Cole M; Carette, Jan E; Chan, Francis Ka-Ming; Bertin, John; Gough, Peter J; Mocarski, Edward S; Kaiser, William J.

Mol Cell ; 56(4): 481-95, 2014 Nov 20.

Artigo em Inglês | MEDLINE | ID: mdl-25459880

13.

Suppressed expression of oxidoreductin-like protein, Oxidor, increases follicle degeneration and decreases survival during the overwintering diapause of the mosquito Culex pipiens.

King, Bryan; Ikenga, Arinze; Larsen, Mazie; Sim, Cheolho.

Comp Biochem Physiol A Mol Integr Physiol ; 257: 110959, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-33862219

14.

Promoter demethylation of the asparagine synthetase gene is required for ATF4-dependent adaptation to asparagine depletion.

Jiang, Jie; Srivastava, Sankalp; Seim, Gretchen; Pavlova, Natalya N; King, Bryan; Zou, Lihua; Zhang, Chi; Zhong, Minghua; Feng, Hui; Kapur, Reuben; Wek, Ronald C; Fan, Jing; Zhang, Ji.

J Biol Chem ; 294(49): 18674-18684, 2019 12 06.

Artigo em Inglês | MEDLINE | ID: mdl-31659118

15.

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.

Ntziachristos, Panagiotis; Tsirigos, Aristotelis; Welstead, G Grant; Trimarchi, Thomas; Bakogianni, Sofia; Xu, Luyao; Loizou, Evangelia; Holmfeldt, Linda; Strikoudis, Alexandros; King, Bryan; Mullenders, Jasper; Becksfort, Jared; Nedjic, Jelena; Paietta, Elisabeth; Tallman, Martin S; Rowe, Jacob M; Tonon, Giovanni; Satoh, Takashi; Kruidenier, Laurens; Prinjha, Rab; Akira, Shizuo; Van Vlierberghe, Pieter; Ferrando, Adolfo A; Jaenisch, Rudolf; Mullighan, Charles G; Aifantis, Iannis.

Nature ; 514(7523): 513-7, 2014 Oct 23.

Artigo em Inglês | MEDLINE | ID: mdl-25132549

16.

Critical role for PI3-kinase in regulating the use of proteins as an amino acid source.

Palm, Wilhelm; Araki, Jingwen; King, Bryan; DeMatteo, Raymond G; Thompson, Craig B.

Proc Natl Acad Sci U S A ; 114(41): E8628-E8636, 2017 10 10.

Artigo em Inglês | MEDLINE | ID: mdl-28973876

17.

An exploration of concomitant psychiatric disorders in children with autism spectrum disorder.

Lecavalier, Luc; McCracken, Courtney E; Aman, Michael G; McDougle, Christopher J; McCracken, James T; Tierney, Elaine; Smith, Tristram; Johnson, Cynthia; King, Bryan; Handen, Benjamin; Swiezy, Naomi B; Eugene Arnold, L; Bearss, Karen; Vitiello, Benedetto; Scahill, Lawrence.

Compr Psychiatry ; 88: 57-64, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30504071

18.

Psychiatric comorbidities in neurodevelopmental disorders.

King, Bryan H.

Curr Opin Neurol ; 29(2): 113-7, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26840045

19.

Children with autism spectrum disorder and social skills groups at school: a randomized trial comparing intervention approach and peer composition.

Kasari, Connie; Dean, Michelle; Kretzmann, Mark; Shih, Wendy; Orlich, Felice; Whitney, Rondalyn; Landa, Rebecca; Lord, Catherine; King, Bryan.

J Child Psychol Psychiatry ; 57(2): 171-9, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26391889

20.

Dendritic cell-based therapeutic vaccine elicits polyfunctional HIV-specific T-cell immunity associated with control of viral load.

Lévy, Yves; Thiébaut, Rodolphe; Montes, Monica; Lacabaratz, Christine; Sloan, Louis; King, Bryan; Pérusat, Sophie; Harrod, Carson; Cobb, Amanda; Roberts, Lee K; Surenaud, Mathieu; Boucherie, Céline; Zurawski, Sandra; Delaugerre, Constance; Richert, Laura; Chêne, Geneviève; Banchereau, Jacques; Palucka, Karolina.

Eur J Immunol ; 44(9): 2802-10, 2014 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-25042008

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